Swiftly get sections as skinny or thick as your application demands, with out worrying about getting rid of or distorting precious tissue samples.
Megatome is a vibrating microtome meant to part a broad selection of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables significant-throughput tissue sectioning with uniform area profile, together with negligible tissue hurt and information decline.
Request a estimate or demo Uniformly area massive tissues & sample arrays Megatome is the only microtome which can area samples as large as intact nonhuman primate and human organs, which makes it invaluable for fields for instance neuropathology.
Running the CLI directly from a Gradle endeavor will not be at this time supported. A distribution should be designed via gradlew :j2d-cli:distZip to make a zip file that contains every thing necessary to operate.
SE utilizes a rotational electrical industry to disperse extremely electromobile molecules (for example antibodies or surfactant micelles) all through a porous sample devoid of harming electrically charged constructions in the tissue. This allows two-four day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them entirely clear. This permits light-weight penetration into your sample and ensures the acquisition of higher-resolution, in-target picture knowledge.
Megatome is really a novel microtome that allows for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue injury and information decline.
It’s time and energy to improve your microtome to Megatome. With accurate superior-frequency slicing for an unmatched choice of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for varied programs.
Entirely delipidate entire mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.
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Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, defending specimens for various rounds of processing.
Leverage the Apparent+ tissue clearing method, coupled with eFLASH and patented stochastic electrotransport systems, to quickly very clear and label complete organs. Essential highlights and capabilities involve:
Our novel SHIELD tissue preservation technique types intramolecular bonds making use of polyfunctional, versatile epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.